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  1. Yesterday
  2. I tried to change but I found that our smoflipid contains microg of Aluminium and we are not only limited by time but also we can't exceed an amount of ml because of Aluminium toxicity We had lipofundin before but it was no more available since the start of COVID-19
  3. Last week
  4. Concord Talk with Ronny Knol and Bram Dees was very inspiring, including some amazing video's that show the actual workflow. you can replay the recording of this Concord Talk via: https://concordneonatal.com/concord-talk/
  5. Great resources, thanks Vicky!!!
  6. Also there are papers now looking at "cooling outside criteria" which are interesting too e.g. late preterms, stroke..... This RCT was in adults but suggests worse outcomes in adults undergoing therapeutic hypothermia who have bacterial meningitis.....https://pubmed.ncbi.nlm.nih.gov/24105303/ A neonatal study (Jenkins et al 2013) has looked at immunosuppressive impact of cooling. Newer possibilities: cooling in NEC?!? https://pediatrics.aappublications.org/content/125/2/e300.short and lots of work now looking at adjunctive therapies like xenon and erythropoetin..... And perhaps
  7. I have only come across this thread too! We (UK) have 48 hour hang times for vamin, and 24 hour lipid change. The lipids are infused on a separate syringe driver, and the vamin run through different fluid pump. We were looking into using orange light protecting giving sets for the lipid which a different colour to our standard giving sets for bags of fluid. We have standard manufactured bags of PN in stock on the unit, and then we can also get special bespoke bags made via our aseptic pharmacy team if the patient needs fluid restriction or careful electrolyte management. Our nurses chang
  8. I think I found an interesting study about antepartum and intrapartum risk factors of neonatal encephalopathy. A bit old, but I think still very relevant when discussing the causes of hypoxic ischemic injury with parents! https://www.bmj.com/content/317/7172/1554.long https://www.bmj.com/content/317/7172/1549.long
  9. This study has lot of limitations: retrospective study, more chronic patients with parents obviously familiarized to their preemies problems, with video laryngoscope use and no nasal TI and only 9,4% of parents If we distribute a questionnaire for stress to parents in acute phase immediately after delivery and later we can maybe realize it would be impossible in the first hours to have parents for suurfactant delivery and immediate care
  10. https://doi.org/10.1186/s12887-020-1958-9 Standardised neonatal parenteral nutrition formulations – Australasian neonatal parenteral nutrition consensus update 2017 I just found this publication in BMC pediatrics from 2017 and it seems obvious we must all shift to 48 hours for parenteral nutrition and consider it for lipids I remembered this discussion and I am sharing this article It contains other interesting informations
  11. So many to recommend , vital topics . Agree it a good idea to start with RCT TOBY trial/ Cool Cap Here the latest I viewed. Human umbilical cord mesenchymal stromal cells as an adjunct therapy with therapeutic hypothermia in a piglet model of perinatal asphyxia - ScienceDirect https://www.sciencedirect.com/science/article/pii/S1465324920309300 by one Dr.Nicola Robertson et al who working on this field + 10 yrs.
  12. Big topic, and lots of available reads! I would suggest to start off with two review papers, the first one describing long-term outcomes from the key RCTs (like the NICHD and TOBY trials, and the other one about neuroimaging (like a historical overview). https://pubmed.ncbi.nlm.nih.gov/27863707/ https://pubmed.ncbi.nlm.nih.gov/27673422/
  13. Hi, I would like to learn more about hypoxic-ischemic encephalopathy (HIE), can you recommend your favorite articles in the topic? I can totally read some reviews, or also original research papers if you think they are well written and relevant animal studies can also be interesting! Thanks!
  14. Earlier
  15. This post is special to me. A redemption of sorts. When I was a fellow in Edmonton in the early 2000s my fellowship project was to see whether heliox (helium/oxygen) given to piglets with meconium aspiration syndrome (MAS) would improve ventilation and measures of pulmonary hypertension vs controls. Why heliox? There had been work done with this gas for other conditions and the lower viscosity of the gas (who hasn’t sucked on a helium balloon to see the effect of helium) means that the flow of the gas in a tube is more linear that regular air. Turbulent flow as with air/oxygen mixtures creates
  16. Guest Lecture https://us02web.zoom.us/j/89068687386?pwd=aWtkckI5L04rN2lWV0xsYTB4N2lWdz09 Topic: Outcomes following a comprehensive versus a selective approach for infants born at 22 weeks of gestation Time: Apr 15, 2021 05:00 PM London 0930 PM India UAE 0800PM We would like to invite you for a talk on Outcomes following a comprehensive versus a selective approach for infants born at 22 weeks of gestation Professor Carl Backes Dr Omid Fatih Departments of Pediatrics and Obstetrics & Gynaecology, The Ohio State University Wexner Medical Center, Columbus, Ohio
  17. I like the underlying principal, that we shall empower and engage parents. I see the major take-home message as being how few parents were present, something that can certainly be improved. From a methodology perspective, I think there are some major limitations (I know, I take the role as Reviewer #3 now...😞 the cohort is from 2014-7, so the findings may (hopefully!) be outdated, that more parents are present nowadays the association between parental presence and the lack of positive or negative impact on intubation outcomes: this may be baised by differences in who the profession
  18. @M C Fadous KhalifeWhat about the paper itself? How do you evaluate the evidence there?
  19. I like the idea, Believe it has benefits, but I am sure it is very disturbing to my staff
  20. Great idea to have a journal club. Currently although parental presence is encouraged it occurs very seldom in our units.
  21. A one day virtual course providing the essential skills to perform and interpret neonatal cranial ultrasound scans on the neonatal unit. This course will cover: · How to use an ultrasound scanner and get the best quality images · Standard images and normal anatomy · Germinal matrix and intraventricular haemorrhage · Linear measurements of ventricular dilatation · Preterm white matter abnormalities · HIE and Doppler measurements · Perinatal stroke Fee: full rate - £50.00 Register here: http://training.ucheducationcentre.org/home/viewcourse/515/
  22. @Vicky Payne- this is a really good question. It has reminded me of a blog entry I "committed" some time ago- not about intubation in presence of family, but about intubation on parent's chest 🔥🔥🔥 link is here below ⬇️⬇️ Of course, the level of evidence is anecdotal, but it's just a reminder for me that the impact on parents could be related to their very unique situation in the Unit. Are they only infrequent visitors there, or maybe primary caretakers? I think that might change their perspective a lot!
  23. Do you think the evidence provided in this paper would change your practice @Francesco Cardona? @bimalc makes a good point about parent choice and options- has anyone asked them (parents) what impact this might have on them?
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  • Latest Posts

    • I tried to change but I found that our smoflipid contains microg of Aluminium and we are not only limited by time but also we can't exceed an amount of ml because of Aluminium toxicity  We had lipofundin before but it was no more available since the start of COVID-19
    • Concord Talk with Ronny Knol and Bram Dees was very inspiring, including some amazing video's that show the actual workflow. you can replay the recording of this Concord Talk via: https://concordneonatal.com/concord-talk/
    • Great resources, thanks Vicky!!!  
    • Also there are papers now looking at "cooling outside criteria" which are interesting too e.g. late preterms, stroke..... This RCT was in adults but suggests worse outcomes in adults undergoing therapeutic hypothermia who have bacterial meningitis.....https://pubmed.ncbi.nlm.nih.gov/24105303/ A neonatal study (Jenkins et al 2013) has looked at immunosuppressive impact of cooling. Newer possibilities: cooling in NEC?!? https://pediatrics.aappublications.org/content/125/2/e300.short and lots of work now looking at adjunctive therapies like xenon and erythropoetin..... And perhaps a topic for a separate discussion thread....and I think topical to practice (in UK) cooling in mild HIE?!?  https://fn.bmj.com/content/105/2/225.abstract?casa_token=urlRBLGeNVgAAAAA:mpPfBX_gPwzVlNLIpUYO9ETpCgdI20zJNzxhuJ2EoqU-hcqW3NGeoqpYXAH9GN-6fZrhsSx-mRk
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