Posted September 12, 200717 yr We are starting to make babies in our NICU NPO during blood transfusions to reduce the risk of NEC. Does anyone have any opinions on this matter, or follow the same practice?
September 17, 200717 yr comment_757 We also don't. And we do not observe higher incidence of NEC that could be connected with feeding during blood transfusion.
September 27, 200717 yr As far as I know there is no evidence that keeping babies NPO during blood transfusion will reduce the incidence of NEC. Are you intersted in doing a RCT? do you have some lab animal data or observational studies?
October 11, 200717 yr comment_793 And btw , what is the theoretical background for not feeding the baby during blood transfusion? I mean, why should it cause NEC?
March 29, 200916 yr comment_1859 We continue to feed babies during a blood transfusion also. As far as I know there is no reason why the baby should develop NEC. However, if the baby is being transfused for increasing apneas and bradys and is unwell, we do check the crypt antigen status before transfusing, since a positive crypt antigen can indicate that the baby already has NEC. Joan
April 4, 200916 yr comment_1879 We have also started with keeping babies NPO 3 hours prior to and 6 hours post transfusion. I believe the theory which has been theorized but no actual clinical trials performed, is that of a reperfusion injury to the gut. We have had several cases in our NICU of otherwise stable kids developing bloody stools and a pneumatosis picture on UB hours to even several days post transfusion, We have adopted an NPO approach in our practice.
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