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selvanr4

hepatic vein thrombosis

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We recently had a newborn referred with hepatic vein thrombosis. Baby had blood and mucoid stools. The total count was high and hence blood c&s sent and commenced with i v antibiotics.symptoms abated. no organism grown in culture. We were hesitant to start LMW heparin because of diverse opinions.But continued with iv antibiotics. Rpt ultrsound showed developing collaterals.

What is the probability that the child will /will not have chronic liver disease. Can  LMW Heparin melt away the thrombosis?

thanks

selvan rathinasamy

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@selvanr4 As I have understood, the etiology is commonly unknown (although UVC is a risk factor) and the outcome is generally also good. Given that liver function is maintained reasonably well, the liver and venous flow will recover over time (recann or new routes)

To my knowledge, anticoagulation is not know to work.

I have this article in my collection, I guess there are newer reviews out there though: https://www.ncbi.nlm.nih.gov/pubmed/21925985 

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