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Stefan Johansson

"Brain sparing" - does it really spare the brain?

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This paper was recently published in J of Pediatr, read it Thanks to @EBNEO that promoted it in this tweet.

 

The headline and study question are both great, but I am sceptical to the design: SGA infant with brain sparing was (as I See it from my vacation balcony in Greece :) ) compared with a small group of term AGA infants. (96 + 32 infants)

Not surprisingly, this small study found mostly no differences.

but as you know - abscense of evidence is not evidence of abscense.

would have been better if SGA infants with brain  sparing had been compared with SGA infants without it (or study whether degree of SGA would be associated with outcomes). Not supernew (has been done before if I recall it correctly) but still relevant to replicate

Below - URL to the paper in J of Pediatr

www.jpeds.com/article/S0022-3476(17)30781-3/

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