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Stefan Johansson

Physiological-based cord clamping (PBCC) in preterm infants. Experiences of resusc with intact cord?

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While preparing a lecture on the normal transition from intra- to extrauterine life, I also choosed to include a slide on cord-clamping, and the timing of it.

As the umbilical vein blood contributes significantly to the systemic cardiac output  (through shunting of umbilical vein blood through foramen ovale), there is a physiological reason to clamp/cut the cord once breathing is initiated.

While reading up on some details, I came across a feasibilty study on a resuscitation table intended for preterm infant: https://fn.bmj.com/content/early/2018/10/03/archdischild-2018-315483

Just recently - this research group also published that this approach of physiological-based cord clamping (PBCC) do increase cardiac output and cerebral oxygenation. Proxy outcomes, but still shows that the concept seems right: https://fn.bmj.com/content/103/6/F530

Just curious to hear: does anyone have experience from stabilization with intact cord (preterm or term)?

Update: also found this review by the same research group: https://fn.bmj.com/content/103/5/F493, also published in ADC FN.

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