September 22, 200817 yr It's not the first time we have isolated P. Aeruginosa from pulmonary mucus in intubated preterms. Everytime we have this germ, we asked ourselves the same question: Is there enough evidence to treat with antibiotics to this preterm babies with a cronic lung disease, if there isn't a bloodstream infection and the child evolution is good?
September 22, 200817 yr Hi I think that when there is not enough argumentation of acute infection such as new clinical signs, inflammation (Procalcitonine or CRP) you have not to treat colonisation. the quality of the bacteriological sample especially the dilution is important for reading correctly the result (amount of P.A. in CFU/ml). Ammar Khaldi Children's hospital of Tunis - Tunisia
September 23, 200817 yr We would do the same; not to treat "pure" colonization, but keep the positive cultures in mind if clinical symtoms arise
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