aerosolized iloprost in PPHN

[ATEFSHAFEI]

We have tried most of treatment modalities in a resistant case of PPHN-including iNO,sildenafil,inotropic support,PG,and eventually iloprost-aerosolized form-....it worked well on conventional dragger 8000 but unfortunately DID NOT on sensormedics.....a technical diffculty-I guess-because of different flow rate..

could you tell me your experience of using iloprost with sensormedics!!!

thanks.

atef

[rehman_naveed]

Since we have now a poll going on regarding management of PPHN so I decided to respond to this question asked by one of our colleague.

Currently we are managing one such patient in which all above modalities failed and we tried iloprost (prostacyclin) via ultrasonic nebulization and it works very well. we gave it via Pressure control mode of mechanical ventilation not when the patient on sensor medics. Unfortunatley we have no IV form available because the protocol says after nebulization form when the patient improve should be switched to IV form.

Our patient is doing well so far with good saturations and decreased oxygen requirement and pressure. Hoping that we will be successful in in weaning from ventilator slowly