Jump to content


Want to join the discussions?

Sign up for a free membership! 

If you are a member already, log in!

(lost your password? reset it here)

99nicu.org 99nicu.org

Covering TPN solutions


Recommended Posts

A number of researchers have demonstarted that covering TPN solutions would decrease peroxide load. We have just finnished a RCT in our institution and we had similar reults. We are updating our guidelines and we are searching for other institutions guidelines

Link to comment
Share on other sites

  • 4 months later...
  • 1 month later...
Guest nicurn2083

We use dark opaque brown bags to cover TPN in our NICU. They help to protect mutliple additives from photo-oxidation.

Jennifer Tucker RN


Minneapolis, MN

Link to comment
Share on other sites

  • 3 months later...
Guest jwalden

Yes, we use the amber plastic bags as well to cover the TPN. TPN arrives from Pharmacy in these bags, and once hung the amber bag is slipped over the TPN bag to keep it covered.

Link to comment
Share on other sites

  • 2 weeks later...

Please refer to the following articles:

1- Chessex P, Harrison A, Khashu M, Lavoie JC.

In preterm neonates, is the risk of developing bronchopulmonary dysplasia

influenced by the failure to protect total parenteral nutrition from exposure to

ambient light?

J Pediatr. 2007 Aug;151(2):213-4.

2: Khashu M, Harrison A, Lalari V, Gow A, Lavoie JC, Chessex P.

Photoprotection of parenteral nutrition enhances advancement of minimal enteral nutrition in preterm infants.

Semin Perinatol. 2006 Jun;30(3):139-45.

3: Lavoie JC, Rouleau T, Gagnon C, Chessex P.

Photoprotection prevents TPN-induced lung procollagen mRNA in newborn guinea pigs.

Free Radic Biol Med. 2002 Aug 15;33(4):512-20.

4: Chessex P, Laborie S, Lavoie JC, Rouleau T.

Photoprotection of solutions of parenteral nutrition decreases the infused load as well as the urinary excretion of peroxides in premature infants.

Semin Perinatol. 2001 Apr;25(2):55-9. Review.

5: Laborie S, Lavoie JC, Chessex P.

Increased urinary peroxides in newborn infants receiving parenteral nutrition

exposed to light.

J Pediatr. 2000 May;136(5):628-32.

6: Baird LL.

Protecting TPN and lipid infusions from light: reducing hydroperoxides in NICU


Neonatal Netw. 2001 Mar;20(2):17-22. Review.

7: Lavoie JC, Belanger S, Spalinger M, Chessex P.

Admixture of a multivitamin preparation to parenteral nutrition: the major

contributor to in vitro generation of peroxides.

Pediatrics. 1997 Mar;99(3):E6.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...