We routinely use the bag in the incubator for the first week in our ELBW. Our impression is that babies are more stable with it. I am not aware of any clinical trials showing efficacy though.

I also recommend Keith Barrington's comment in his blog on erythropoietin in asphyxia https://neonatalresearch.org/2016/05/09/erythropoietin-for-asphyxia/

It is about the most recent phase II study on this topic published last year.

Great link @Stefan Johansson!

Great news, Andrej!

@Andrej Vitushka this course might be a bit on short notice for you: http://tinec.org/

It is already next week January 26-28, 2017 in Lausanne, Switzerland.

Here is the link for lazy people like me :-) to the blog post:

the PDA: why should we treat it? how should we treat it? when should we treat it? or should we treat it at all?

I would like to see some nursing topics at the conference. Any ideas?

Here is some literature on the subject:

http://www.ncbi.nlm.nih.gov/pubmed/27222450?dopt=Abstract

Quote

Int J Nurs Stud. 2016 Jul;59:51-9. Heparin versus 0.9% sodium chloride intermittent flushing for the prevention of occlusion in long term central venous catheters in infants and children: A systematic review. Bradford NK(1), Edwards RM(2), Chan RJ(3).

On 28.6.2016 at 10:12 PM, Stefan Johansson said:

 @fcardona Any ideas about speakers on those topics?

Predicting outcome - Either you could go for some neuropediatrician, neuroradiologist or ethicist - all choices could be interesting

I always find some topic on inborn errors of metabolism interesting, any new developments in this field?

Topic: Early prediction of preterm outcome - what do we know? what dont we know?

If we continue with low rate infusion, we add heparin to the infusion solution 2 IE/kg/h. I am not really sure that makes sense.

I am curious. Do you lock your central venous catheters which are not in use? How often do you change the lock?

Sounds great!

Will there be an android version, too?

Interesting topic. I have always wondered about the scientific base of the 5-IB approach. Would be interesting to find out more on the use of either method.

There is a study in rabbits comparing different flows with HFO which did not find any difference in effect with different bias flows (cant find the citation at the moment).

In a course on HFOV they mentioned that there is no evidence to say which ratio would be more efficient for ventilating patients (Van Kaam).

Thanks for the link!

We use I:E of 1:1 with the Fabian (we also used 1:2 ratio with Sensormedics). The company suggests to use 8 lpm of bias flow for HFO.

Thats what I had remembered as well - thanks for the link!

I did not find anything related to newborns and stress-related mucosal disease. There is weak evidence for PPI to prevent gastric bleeding in pediatric patients http://www.ncbi.nlm.nih.gov/pubmed/19770788

PPI at least seem to be effective in achieving higher gastric pH levels in neonates http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616221/ and http://www.ncbi.nlm.nih.gov/pubmed/17204951/ although best dosing advice seems elusive.

We have been discussing this on our ward. Should we provide therapy to prevent SRMD ( stress-related mucosal disease) in our neonates that are ventilated, do not get any feeds or are otherwise severly ill?

And what therapy do you believe is best?

If you know any current evidence please share it!

I totally agree this is an absolute recommendation for any neonatal staff. It shows how much we still need to learn about outcomes and how to predict outcomes better.

Interesting read indeed!

I wonder if that means that we will see placebo-controlled trials in PDA studies in the future..

We use an excel-file with our medications we could use as a list to start with.

Further thoughts: a pharmacologist?

I agree with the posts above. The first step is to recognize the possible etiology of malnutrition.

Possible mechanisms in the setting of cardiac patients are:

• inadequate intake
• poor absorption
• increased loss
• increased demand
• decreased growth potential
• extracardiac factors

The list is taken from here:

Nutrition and Heart Disease: Causation and Prevention

edited by Ronald Ross Watson, Victor R. Preedy

https://books.google.at/books?id=d8AzJo5FE3gC&lpg=PA260&ots=RqedD0iB1B&dq=cachexia cardiac infants&pg=PA255#v=onepage&q=cachexia cardiac infants&f=false

Interesting point on "early stylet removal", had not heard that before.

I cant talk about any own experience, but I know some physicians use these ventilators:

https://www.hamilton-medical.com/en_IN/Products/Mecanical-ventilators/HAMILTON-T1.html

http://www.acendis.eu/acendis/products/product.php?pid=68&cid=6&p=Heinen+%2B+L%F6wenstein&frompage=producers

This one is very basic (we still use it at our ward..) but cant ventilate in synchrony among other issues:

http://www.smiths-medical.com/catalog/mechanical-ventilation/pneupac/baby-pac/pneupac-babypac.html