Dose & administration
10-15 mg/kg/dose given intravenously per the following interval recommendations, and directed/adjusted by serum concentration measurements:
Postmenstrual age (PMA)
≤29 weeks PMA: 0-14 days postnatal age, dosing interval = 18 hours; >14 days postnatal age, dosing interval = 12 hours
30 to 36 weeks PMA: 0-14 days postnatal age, dosing interval = 12 hours; >14 days postnatal age, dosing interval = 8 hours
37 to 44 weeks PMA: 0-7 days postnatal age, dosing interval = 12 hours; >7 days, dosing interval = 8 hours
≥45 weeks PMA: all p
