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Weaning of nCPAP. How low do you go?

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Studies show that there are more benefits with weaning nCPAP by decreasing pressure than having alternating "time-on and time-off" nCPAP.

We wean by lowering the pressure gradually, in the preterm to as low as 2cm H20.

I know that many use 4cm H20 as a lower limit.

The argument for this is that the pressure measured in the pharynx is close to zero when CPAP is set lower than 4 cm H20 (thus believed to not have any positive effects).

Still, we see many babies that benefit from low pressure CPAP (2-3).

Do you know any studies that show negative effects using low pressures? (Theoretically, it could give increased breathing effort without any significant CPAP effect).

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