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Treatment For Atypical Bacterial Infection

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We frequently see mothers who are colonised with Ureaplasma and for that receive ABx with Erythromycin (with +/- success). Having a baby on the unit who was born preterm due to AIS caused by Ureaplasma (PCR confirmation) the old discussion about treatment of atypical bacterial infection in neonates was re-ingnited. Usually these infants receive a course of clarythromycin PO, however, the suspension causes frequent obstruction and thus requires replacement of the NGT.

The data are still controversal about the requirement to treat these kind of infections.

Therefore I would be interested in your practices, do you test, do you treat, if so, with what (macrolide ...) and how (po, iv) and for how long do you treat?

 

Thanks!

 

  • 3 weeks later...

1.we don't test  but treat if c&s negative and the baby is sick.

2. azithromycin 10 mg /kg (oral) or 5 mg/ kg ( iv)

3.3 days.

 

we do not know whether all babies were benefited but it is worth trying.

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