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Infectious Diseases

  1. This paper (video abstract below!) came on my radar recently, that antibiotic stewardship works in the NICU, that initiation of antibiotics is reduced, length of tx is reduced etc. A recent UK paper is a nice example of this, although most preterm infants in this paper still recieved antibiotics I think we are pretty restrictive with antibiotics (as illustrated by this paper), but I feel we could have a more systematic approach... How do you tailor antibiotics, and what tools do you use? what makes you start? what makes you stop?

  2. Hello everyone! In Austria we are facing an Ampicillin Shortage - I suppose this will be the same in whole Europe. As iv Amoxicillin is not common available, too, the question about the best alternative arises. Any thoughts on good alternatives to pair with an amonoglycoside? Or another combination? A possible empiric therapy would be Pip/Taz, but that would be too broad already, right? Would a combination of Flucloxacillin with Gentamicin or Tobramycin be enough? thank you for your thoughts! best wishes bernhard

  3. Started by Amirmasoud Borghei,

    hi.what is the alternative ampicilin in nicu!?for early and late sepsis

  4. Started by neonate,

    Good afternoon members, I have a strange issue. I have received a 6 weeks old infant, transferred from another hospital, normal vaginal delivery to a G2 P2 mother, with no significant antenatal history(heresay), birth weight being 2.5kg, no other anthropometry available. Baby was discharged but taken to the hospital in view of poor feeding, admitted with a diagnosis of sepsis based on thrombocytopenia(48,000), high CRP but negative culture. Hewas discharged after 5 days of iv cefipime but returned to the hospital after 10 days with breathlessness. He was again investigated, found to be thrombocytopenic and anemic and was transfused with platelets and packed cells, u…

  5. Guest danielirra
    Started by Guest danielirra,

    Dear all, I need your feedback regarding the importance of maternal hepatitis B results to administer HBIG as soon as possible (ie if the delay 48-72 hours could diminish the effectiveness in preventing HB) We have some problems during the weekend with our laboratory. thanks in advance Daniel

  6. Started by ali,

    Hi 99ers, Those LBW preterm infants with PICC lines for parenteral fluids, do you perform routine CRPs/infection markers in the otherwise well appearing infant? Many thanks Al

  7. Started by Vicky Payne,

    Dear all- I am posting this via the 99NICU app to test it!! But I am also interested to know what strength Chlorhexidine people use prior to central line insertion in ELBW infants and 23 (?22?) to 25 weeks??? Thanks in advance! Best wishes Vicky x

  8. This might be useful to some, covers paediatrics and some neonates. "Waiting until 48 hours to stop antibiotic therapy in all children is an outdated approach. Research shows that 90% of bacteria will have grown by 24 hours and 95% by 36 hours. In children with low BSI suspicion, stopping antibiotics at 24–36 hours with good safety-netting advice avoids unnecessary hospitalisation without jeopardising patient safety" https://ep.bmj.com/content/edpract/106/4/244.full.pdf Just for fun.......anyone stopping at 24 hours?

  9. In case the mother serology unknown, what are you doing in case of extreme premature babies than 1000g?? Are you give HBIg and vaccine to these babies within 12 hr Sent from my Redmi Note 9 Pro using Tapatalk

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  10. Hi everyone ! CMV controversy again - who performs systematic CMV screening in pregnancy? - does anyone give antiviral drug (valaciclovir) during early pregnancy in case of maternal primary infection, in order to prevent vertical transmission? https://www.sciencedirect.com/science/article/abs/pii/S0140673620318687?via%3Dihub

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