Jump to content


Want to join the discussions?

Sign up for a free membership! 

If you are a member already, log in!

(lost your password? reset it here)

99nicu.org 99nicu.org

Phenobarbital Shortage

Recommended Posts

Hi Everyone!

Our Pharmacy told us, that there is an rising shortage of phenobarbital. Being 1st line treatment for neonatal seizures again, this brings some problems with it.

What would you prefer as 1st line treatment instead?

- Guidelines are kind of favouring Phenytoin as an alternative - but has more significant sideefects.

- Levetiracetam? Not that promising, right?

Any alternatives?


Best wishes, Bernhard

  • Like 1
Link to comment
Share on other sites

Thanks you for your answers.


we used LEV for 1st line therapy for some years, but often ended up with a co-therap with phenobarbital, so we switched back to pheno as 1st line at the time the new ILAE Recomendatilns came out.


so now we will do LEV as 1st line after temesta for acute therapy and Phenytoin as 2nd line, in case phenobarbital really is getting non available.


thank you for your reply

  • Like 1
Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...