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Below are the canadian and american recommendations for surfactant administration. Hope that will answer your first question.

Recommendations for neonatal surfactant therapy.

Fetus and Newborn Committee, Canadian Paediatric Society (CPS)

Paediatr Child Health. 2005 Feb;10(2):109-16

LINK TO DOWNLOAD

LINK TO READ

Surfactant-replacement therapy for respiratory distress in the preterm and term neonate.

Engle WA; American Academy of Pediatrics Committee on Fetus and Newborn.

Pediatrics. 2008 Feb;121(2):419-32.

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