Respiratory Disorders

Hi everybody, I would like to ask about the I:E ratio in an HFO-VG setting in case of ELGANs. Do you use an I:E ratio of 1:1 or 1:2 in HFO-VG on the VN800 for ELGANs 22-23 wks below 500g BW? Also would you worry of causing atelectasis using an I:E ratio of 1:2 when the infant is on low MAPs like 8 or 9 cmH2O, Frequency of 12Hz at DOL10 ?

Hello everyone, I am a third-year medical student from Brazil and we recently discussed an insightful retrospective study published in the Journal of Perinatology titled Don't Wait, Vaccinate. It compared the incidence of cardiorespiratory events in preterm infants receiving all routine 2-month vaccines on a single day versus on multiple days. The study found no significant difference in events like prolonged apnea or bradycardia between the groups. Single-day administration, however, reduced schedule interruptions, improving adherence to vaccination timelines. I'd like to hear your thoughts: Have you observed differences in outcomes with single-day…

I apologise if this topic has already been covered. We’re currently discussing severe BPD cases, particularly infants who remain in the NICU beyond a corrected age of 44+0 weeks, with some even nearing six months. These prolonged stays bring unique challenges, such as the need for specialised training, appropriate equipment, and specific emergency protocols. For example, if a baby at a corrected age of four months experiences a collapse, should the team initiate resuscitation using an NLS/NRP approach, or should an APLS code be applied? In my experience, only one unit had a clear policy to guide these situations. I’d be very interested to hear how your units h…

This came on my radar, a systematic review about BPD rates. Nothing really new, but a good baseline paper to reference. https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-024-02850-x

Hi 99ers, Do you regularly use Budesonide nebs in the preterm population? If so what guides your use ( FiO2, mode of support, CXR changes ) and if so what is the length of the course (days or weeks). Not sure the evidence is there but it is becoming more prevalent. Thanks, have a good weekend 👍 Ali

This paper came on my radar, UK data on 83.000 very preterm infants born 2010 to 2020, and their mortality and respiratory outcomes. The short version is that mortality decreased from 10.1% to 8.5% while severe BPD increased from 12% to 17%. The composite of death/severe BPD changed from 21% to 24%. Also postdischarge respiratory support increased between 2010 and 2020, from 13% to 17%. The authors write in their conclusion that "these survivors will develop chronic respiratory diseases requiring greater healthcare resources." What's your thoughts in this paper? What shall we do?! Find the full-text paper here: https://thorax.bmj.com/content/early/202…

Hi guys! What's your first choice of ventilation suport for extreme preterm babys after delivery Room? nCPAP, NIPPV or HFNC? Most places I know uses nCPAP. But, the last Cochrane Review (2017) about this issue states that NIPPV reduces respiratory failure and need for intubation, without worsening of adverse effects. Any thoughts? The same goes for post extubation treatment..

Greetings all. Sometimes we have to change caffein to aminophylin and vise versa (due to availability issues). Do you use a loading dose when you change it? Or continue just with maintenance dose? thank you so much