The main reason to start with room air is the fear of having ROP or increased incidence of BPD/CLD. Oxygen is not the only factor in causation. At the other end the prematures have already a fragile brain which can easily be damaged by improper resuscitation and proper oxygenation is an important factor for a successful resuscitation. We usually start with 100% oxygen but within minutes as the saturation improves, bay is administered blended oxygen mixed with air. We still have to report a case of ROP in our NICU where we have successfully resuscitated babies from last one decade. This seems opposite to Australian guidelines where room air is advised as a starter and gradually the oxygen percentage may be increased.