There is a very good lecture available as a web cast:

professor Nick Evans and "Diagnosis and treatment of PDA - important clinical implications"

The company Orphan-europe provides the web cast: you may need to register at

http://www.pda-solutions.eu/

(but... I could also connect directly using the link:

http://www.orphan-webcast.com/viewer/?presentation=64 )

thanks Stefen,it is very good lecture.