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Indomethacin for IVH prevention in preterm infants

Have you or do you still use indomethacin prophylaxis to prevent IVH? 54 members have voted

  1. 1. Have you or do you still use indomethacin prophylaxis to prevent IVH?

    • Yes, we still use indomethacin prophylaxis.
      21
    • No, but we used it before 2010.
      31
    • No, and we have never used it.
      101
    • Other reply (please comment below).
      5

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Featured Replies

Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.

(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.

(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

  • 2 months later...
Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.

(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.

(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

  • 3 weeks later...

IS Indomethacin available in your units? Here in the UK, it has not been available for use ( we used it for PDA prohylaxis before 2010 but cannot anymore mainy because of non availability)

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