Indomethacin for IVH prevention in preterm infants

1. Have you or do you still use indomethacin prophylaxis to prevent IVH?
- Yes, we still use indomethacin prophylaxis.
  
  21
- No, but we used it before 2010.
  
  31
- No, and we have never used it.
  
  101
- Other reply (please comment below).
  
  5

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Posted June 2, 201311 yr

Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.

(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.

(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

2 months later...

August 23, 201311 yr

Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.
(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.
(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

August 23, 201311 yr

No as fluid restriction is good,we are practicing fluid restriction from last 10 yrs without any complication

3 weeks later...

September 8, 201311 yr

IS Indomethacin available in your units? Here in the UK, it has not been available for use ( we used it for PDA prohylaxis before 2010 but cannot anymore mainy because of non availability)