Indomethacin for IVH prevention in preterm infants

[99nicu.org]

Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.

(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.

(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

[jagdish1313]

Prophylactic treatment with indomethacin was shown to reduce the risk of severe IVH in the 1990s.

(http://www.ncbi.nlm.nih.gov/pubmed/8134206)

However, follow-up studies later showed that indomethacin prophylaxis did not improve mortality or neurodevelopmental outcomes. These findings are summarized in a Cochrane review from 2010.

(http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000174.pub2/abstract)

The 99nicu Poll for June and July is about such NSAID prophylaxis and whether you have and/or still use it.

[jagdish1313]

No as fluid restriction is good,we are practicing fluid restriction from last 10 yrs without any complication

[Neon8al]

IS Indomethacin available in your units? Here in the UK, it has not been available for use ( we used it for PDA prohylaxis before 2010 but cannot anymore mainy because of non availability)