99nicu Poll: magnesium sulfate and preterm labour/birth

Magnesium sulfate, given to mothers in preterm labour, has been suggested to improve neurological outcomes for preterm infants.

However, ,&do=embed' frameborder='0' data-embedContent> long term follow-up studies has not been confirmative.

Similar to one of the major publications in 2003 (in JAMA), principally showing trend towards better short term outcomes, those did not find associations with statistical significance, although absolute numbers of outcome events were more common among infants given placebo.

In other words one could interpret these findings in two ways:

1. statistical power may have been too low to detect differences

2. the non-significant "trends" are random findings

It would be interesting to hear about your practise regarding magnesium sulfate - please participate in the poll and comment below!