Sildenafil duration on post ECMO CDH neonates

[LIA GRAVARI]

Hello everyone,

about 95% of our post ECMO CDH repaired babies end up on sildenafil

Some of the cardiologists advocate leaving sildenafil on until outpatient follow up and up to 2 years of age regardless of ECHO findings but some stop as soon as the 1 month post repair ECHO shows no pulmonary HTN

What is your institutional experience?

Thank you,

LIA IORDANOGLOU

[Francesco Cardona]

There is an ongoing study (in EU, Canada, Australia) trying to help with this question: https://bmjopen.bmj.com/content/9/11/e032122

I have seen both happen - short therapy and longer therapy with sildenafil.