Jump to content

JOIN THE DISCUSSION!

Want to join the discussions?

Sign up for a free membership! 

If you are a member already, log in!

(lost your password? reset it here)

99nicu.org 99nicu.org

Leukemoid reaction in a non-down pretrerm infant. What causes it?


abeluchin

Recommended Posts

A 29 2/7 weeks male infant was born two days ago from a 25 y/o G1P0 healthy pregnant mom. MOC showed up in preterm labor, with PPROM, and infant was born by CS due to NRFHT. Apgars 2 and 8. Infant intubated at delivery, given curosurf and weaned from the vent over 6hours. Tolerated HFNC at 5 lpm, on 20's FiO2. Amp and Gent started for suspected sepsis. Maternal serology was negative, (HIV, RPR, GBS). No maternal chorio. A CBC at 24 HOL showed WBC in the 65k, with 19% Bands, 11% myelos, 7% meta. Baby otherwise clinically stable. No phenotypic features of down syndrome.

1- What causes this phenomenum?

2- How log does it ussually last?

30 any reference article of idipathtic LR in this population?

Thanks for your kind help

Link to comment
Share on other sites

  • 3 weeks later...

I have seen leukemoid reactions 4 times in the past 20 years in non-Trisomy 21 babies. TLC > 50k. DLC Polys > 75-80. On three occasions it was gram negative septicemia. In one infant I remember, the counts were 20k in the morning and rose to 45k after 6 hours. In another active baby the count went on increasing over a couple of days (despite being on antibiotics) and eventually the blood culture grew Gm negative bacilli (Can't remember the bug). Only one child had unexplained high counts which settled down over a period of one month

Link to comment
Share on other sites

  • 2 weeks later...
  • 7 months later...

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...