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Hematological Conditions

  1. Any experience with a case of A 21 trisomy, with clinical manifestations of transient abnormal myelopoiesis (TAM) but no blasts detected in the blood? Experiencing a case of late preterm, 21 trisomy, IUGR, serologically -ve for HSV, CMV and Parvovirus infections, anemia, hepatomegaly, elevated transaminase by 10 folds, serum T. bilirubin reaching 15 mg / dl and ascites. Did this scenario justify treating with low-dose cytarabine?

  2. Started by juan carlos vidal,

    Hello group, We continue discussing in our hospital when we would have to suspend phototherapy, According to AAP 2 to 4 mg/dl below the threshold value of the day of start of treatment, this could be good as a reference for patients older than 48 hours, but If we take patients who are admitted within 24 hours of life with values of 8 to 10 mg/dl, not so much What strategy or what values do you use in your hospitals to discontinue phototherapy?

  3. Started by abeluchin,

    Hi I took care of a baby who's mother is B+ and baby is A+ with a DAST/Coombs+. The DAT was sent inarventently since we only sent DAT in mother's with blood tupe O or rh negative. I was surprised to see this results since I have always understand that ABO incompatibility that cause significant hemolysis is only produced when mother is O and baby is A or B group. The reason for this ABO incompatibility set is not too clear. I understand its because when mama is O and baby is A or B; IgG antibodies casn be produced during gestation that will cross the placentas . Unlike when mama is A and baby is B or mama is B and baby is A only igM antibodies are produce yhjat will…

  4. Started by agoz,

    To whom we must give repetetive vitamin k : to which gestational week, limited to taking total parenteral nutrition, limited to taking antibiotics ? When we must give : once a week ? Until which gestational age ?

  5. Started by agoz,

    What is normal level of vitamin B12 in newborn ?

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  6. Greetings to all.. We have some issues that need clarification, at least in neonatology perspective. 1. what is the minimal platelet count for surgery (e.g abdominal surgery) in preterm infant? 2. Do you routinely measure coagulation test before surgery? Especially in preterm infant? 3. Do we have evidence for this? Thank you for your kind attention

  7. HIT: A relatively rare but often quite serious complication of heparin therapy. Only after the little 19 years journey in NICU, found one. Would like to share and discuss the participant members' experience, opinion shading more light into this intriguing topic. Thanks and regards, Fiat Lux : ) Heparin-Induced Thrombocytopenia in Neonates Martchenke2005.pdf Diagnosis and treatment of heparin-induced thrombocytopenia in neonates and children Risch2006.pdf

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  8. In fact i want to have your point of view in the new neonatal screening they want to add in ksa ..to take cord blood sample for direct coomb test in delivery room to all neonate whatever healthy or not ..even if the blood groups of mother and bb are comptable ..if the baby get positive test he is considered for early diagnosis and management of hemolytic diaease caused by incompetability ... what do you think this will add ? I think RH and ABO can be expected ..? Is there any probability to have hemolysis even with comptable bl.groups? Does it really needs to be screened ?

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  9. Started by abeluchin,

    46 days old; former 28 weeker premature baby with persistent leukocytosis for over four weeks now. Uncomplicated NICU course so far. Since about the second week of life, the baby has had persistent leukocytosis with wbc count in the low to high 30k's. Baby has had multiple crp done and all normals. Culture from blood and Urine including fungal normal as well. Had a course of Meropenem for suspected UTI with 10k colonies of enterococcus fecalis in the urine; but despite negative repeat urine culture and after treatment; leukocytosis persisted. About two weeks ago; now baby with mild thrombocytopenia 80-90k. Cardiac echo done, renal and abdominal US all normal. Viral …

  10. Started by juan carlos vidal,

    hello group, I would like to know how your institutions deal with the administration of iron after transfusion.