May 5, 201016 yr Hello, I would like to know the place of recombinant erythropoietin in the management of anemia of extreme preterms (28 weekers). When do we start , whether to wait for the response to iron or red cell transfusion? Do we have a well validated guideline? Because most of the books are not categorical. thanks dr.r.selvan
May 5, 201016 yr Some nice articles on this topic: Mainie P. Is there a role for erythropoietin in neonatal medicine? Early Hum Dev. 2008 Aug;84(8):525-32. Epub 2008 Jul 23. Review. PubMed PMID: 18653293. LINK Aher S, Malwatkar K, Kadam S. Neonatal anemia. Semin Fetal Neonatal Med. 2008 Aug;13(4):239-47. Epub 2008 Apr 14. Review. PubMed PMID: 18411074. LINK
May 6, 201016 yr Cochrane review(2008) of early rHuEPO administration (starting before the 8th day of life) found a reduction in the number of transfusions, the volume of packed red blood cells given, and the number of donors required, but reported a significant increase in the frequency of severe (stages III-V) retinopathy of prematurity
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