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thrombocytopenia and neutropenia alloimmune


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One of our term newborn presented thrombocytopenia (with antibodies

maternal IgG) and neutropenia (with maternal HLA antibodies), hours after transfusion

of platelets and Ig Vena and Neupogen is better. Has anyone had any cases in which

thrombocytopenia is associated with neutropenia? parents are South Americans.


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  • 3 weeks later...

Dear Michelangelo,

Perhaps you have done both the work up for Neutrophil Antibody Screen and HLA (PRA) Antibody Screen.Though very rare but in congenital Wiskott-Aldrich syndrome it's possible to have associated neutropenia along with thrombocytopenia.You can check this repository:

http://eprints.ucl.ac.uk/8520/ [full text is not available].

How is the child anyway?



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  • 1 month later...

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