Maximum TPN osmolarity for central line for preterm infants

[essadr]

What is the maximum TPN osmolarity for central line for preterm infants and please can you send the references.

Thanks,

Essa Al-awad

[Stefan Johansson]

Read this thread about osmolarity. It seems that practises vary, some seem to go as high as 1800 mosmol/l. Personally, I'd not advocate such high osmolarity, even central lines can result in extravasation and a very hypertonic solution i any extravascular space...

http://www.99nicu.org/forum/showthread.php?760-NICU-TPN-OSMOLARITY

Maybe this reference may give you some information about hypertonic solutions:

http://www.ncbi.nlm.nih.gov/pubmed/12389676