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Radhika Maddali

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  1. A 21 Trisomy, IUGR with clinical transient abnormal myelopoiesis (TAM) but No blasts detected in the blood.

    Radhika Maddali replied to Hamed's topic in Hematological Conditions
    Treatment in TAM cases is indicated only in the presence of Life threatening complications: Signs of hyper viscosity → blast count > 100,000/uL, Hepatosplenomegaly causing respiratory compromise Heart failure (ejection fraction - 47% or shortening fraction - 27%) not directly the result of a congenital heart defect Hydrops fetalis Renal or hepatic dysfunction Disseminated intravascular coagulation with bleeding. COG trial: Adapted from Gamis et al, 2011

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