Darya

Hello Stefan and all the members! I have a question about therapy of PDA. In Russia we have neither ibuprofen nor indomethacin, as official registered medication, up till now. That is why we can’t use them commonly. Generally, if we see the hemodynamicaly significant PDA, after some conservative cure, we close it surgically. I am interested how early we must operate? As example, the patient (1000 g, GA - 28W) was on the NCPAP after birth, than he was intubated. On the 2nd day diameter of the duct was 3,5 mm, La/Ao=1,6; on the 3d day(on HFOV) – diameter- 3,0 mm, LA/Ao=1,8. Should we wait for any age, more suitable for operation, not the first days of life? What is your experience?