ernani miura

PCR from blood, urine or CNS will cofirm the diagnosis of CMV congenital infection. Ganciclovir is a very powerful drug to the infection and to the baby. More than 50% will result in neutropenia and trombocytopenia with a dose of 12 mg/kg/d. Probably concomitant use of immunoglobulin-CMV monoclonal would be a gain. There is no experience in congenital CMV with famciclovir PO. Ernani Miura, Porto Alegre, Brazil.

We reduced fungus infection in VLBW using this protocol: premature baby less than 1.250 g with three of these situation, not doing well, prolonged parenteral nutrition with more than 3 g of fat, prolonged mechanical ventilation, cephalosporin of third generation, corticosteroid, B2 blocker, neutropenia and trombocytopenia, independent of blood culture we started amphotecyn IV infusion of 1 mg/kd/d. So we reduced from 5 cases/year to 1 case/year. Ernani Miura, Porto Alegre, Brazil.