Hello 99ers,

how is your experiance with iNO via nCPAP in premies? Do you use it at your ward? We got some good and bad experiances at our Department and i would like some unbiased experiances/opinions from your side before i tell our stories 😀

Best,

Lukas

Am curious to hear your stories later  

We dont have iNO so I have nothing to share. But in term infants we have sometimes used epoprostenol - I shared a story ⤵️

 

We do not have iNO either yet.

But when I was on observership in NICU of Medical University Hospital in Graz (quite close to you ) in 2015, they did iNO to the infant on CPAP. It was a complicated heart defect with persistent pulmonary hypertension. INO was titrated according to SpO2 and daily heart ultrasound. As far as I remember they in increased sildenafil per os aiming to withdraw iNO eventually.  Not so much but hope it helps.

It works very well.

We extubated two patients against CPAP under ongoing iNO therapy. Both patients did fine. CPAP and iNO is probably no option in a severe respiratory failure, but ongoing iNO therapy shouldn't be a reason for no extubation. 

I'm very sensitive to iNO exposure, so I can tell iNO on CPAP with less than 10 ppm are possible, but keep the windows open and the flow as low as possible.