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iNO Administration via nCPAP- any experiance?

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Hello 99ers,

how is your experiance with iNO via nCPAP in premies? Do you use it at your ward? We got some good and bad experiances at our Department and i would like some unbiased experiances/opinions from your side before i tell our stories 😀



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We do not have iNO either yet.

But when I was on observership in NICU of Medical University Hospital in Graz (quite close to you :) ) in 2015, they did iNO to the infant on CPAP. It was a complicated heart defect with persistent pulmonary hypertension. INO was titrated according to SpO2 and daily heart ultrasound. As far as I remember they in increased sildenafil per os aiming to withdraw iNO eventually.  Not so much but hope it helps.

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It works very well.

We extubated two patients against CPAP under ongoing iNO therapy. Both patients did fine. CPAP and iNO is probably no option in a severe respiratory failure, but ongoing iNO therapy shouldn't be a reason for no extubation. 

I'm very sensitive to iNO exposure, so I can tell iNO on CPAP with less than 10 ppm are possible, but keep the windows open and the flow as low as possible.

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