Anyone use hyperconcentrated platelet transfusions?

[Francesco Cardona]

A question reaches us via Twitter by Susanna Fustolo-Gunnink:

 

Are there neonatal intensive care units in which hyperconcentrated platelet transfusions are administered? @EBNEO @ccroehr @DrCGale @NeonatalResearc @cwsbattersby @RizKhanahmed @TimWatts1964 @BSantamaria8 @drpaulclarke @Colin37377735

 

 

[bimalc]

This is perhaps not the answer she was hoping for, but in her own multi center cohort study on bleeding risk and transfusion from 2017 there was at least one center that administered concentrated platelets ... 

[Susanna FustoloGunnink]

Hi Bimalc

thanks for your reply. This is exactly why I am asking, we do have one center where hyperconcentrated platelets are administered, but need more data if we want to assess their effect on clinical outcomes. So I am hoping to find another 3 or 4 centers in which hyperconcentrated platelets are administered, so we can share our data, analyze the results and hopefully generate more reliable evidence regarding the efficacy of this product in neonates. 

[Stefan Johansson]

@Susanna FustoloGunnink thanks for posting here  looking fw to hear and learn more about your experiences. Do you still use hyperconc platelet transfusions?

[Susanna FustoloGunnink]

I don’t work at that particular center, but I know they still use hyperconcentrated platelet transfusions, yes. I guess there is as little evidence for that strategy as there is for giving 15 ml/kg of the normal platelet transfusion product. So we hope to be able to learn from their experience and outcome data.