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Hypocalcemia and phototherapy in preterm baby

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Dear Thabit,

The physiological explation of the hypocalcaemia [Late Onset Hypocalcaemia (LOH)] in preterm neonates receiving phototherapy may be associated with the decreased melatonin secretion [i.e.phx induced] and increasing bone uptake of calcium [John P Cloherty,Eric C Eichenwald,Ann R Stark,Manual of Neonatal Care.Lippencott Williams & Wilkins.Fifth Edition 2004.Chapter 29.Pp 582].

Predisposing physiological factors are succintly described in Fanaroff and Martin's Neonatal Perinatal Medicine,Diseases of Fetus and Infant,Mosby Elsevier,Volume II,8 th Edition 2006,Chapter 47, Metabolic and Endocrine Disorders,Pp 1510 (but in Pp1512 writes "although the mechanism is still uncertain")].



Edited by Sutirtha Roy
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