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EBNEO Commentaries and Articles of the Month

Here, EBNEO publishes #NeoEBM summaries of the best original articles!

  1. Mahmoud Abdelreheem & Hassanein Moustafa from UK review the paper 'Li Y, Wisnowski JL and Chalak L, et al. Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury. Pediatr Res. 2022 Dec;92(6):1731-1736. doi: 10.1038/s41390-022-02026-7. Epub 2022 Mar 30. PMID: 35354930; PMCID: PMC9771796.' for EbNeo. Read Here! ACTA Commentary: Acta Paediatrica - 2025 - Abdelreheem - EBNEO Commentary Mild Hypoxic Ischemic Encephalopathy HIE Timing and Pattern of.pdf "Neonatal hypoxic-ischaemic encephalopathy (HIE) remains one of the leading causes of neonatal mortality and long-term disability worldwide. Infants with mild HIE, representing 50% of all HIE …

  2. Help Select the 2024 EBNEO Impact Article of the Year!The EBNEO Impact Article of the Year (IAOTY) celebrates research that shapes neonatal practice and sparks global discussion. From the Impact Article of the Month (IAOTM), EBNEO editors have selected the eight most impactful articles of 2024, and now it’s the community’s turn to decide which study stands out. The public vote is open for five days, and the two articles with the highest votes will advance to the final round, where the neonatal community will select the ultimate IAOTY winner. Only one vote per participant is allowed; multiple votes will be monitored and removed. This award reflects not only scientific exce…

  3. Gabriel Altit from Canada www.theneocardiolab.com reviews the April Article of the Month "Mazhari MYA, Priyadarshi M, Singh P, Chaurasia S, Basu S. Norepinephrine versus Dopamine for Septic Shock in Neonates: A Randomized Controlled Trial. J Pediatr 2025;282:114599. https://doi.org/10.1016/j.jpeds.2025.114599. PMID 40252959." for ebneo.org. READ HERE! ACTA COMMENTARY: Acta Paediatrica - 2025 - Altit - EBNEO Commentary Review of the Norepinephrine Versus Dopamine for Septic Shock in.pdf "The randomized controlled trial by Mazhari et al. provides valuable comparative data on norepinephrine versus dopamine as first-line agents in neonatal fluid-refractory septic shock1. …

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  4. Narasimha Rao & H Gowda, from UK review the paper "Marlow N, Barrington KJ, ODonnell CPF, Miletin J, Naulaers G, Cheung PY, Corcoran JD, Khuffash E, Boylan GB, Livingstone V, Pons G, Straňák Z, Van Laere D, Macko J, Wiedermannova H, Dempsey EM; HIP consortium. Outcomes of extremely preterm infants who participated in a randomised trial of dopamine for treatment of hypotension (the HIP trial) at 2 years corrected age. Arch Dis Child Fetal Neonatal Ed. 2025 Jan 19:fetalneonatal-2024-327894. PMID: 39832819." for EbNeo.org. READ HERE! ACTA Commentary: Acta Paediatrica - 2025 - Rao - EBNEO Commentary Reevaluating Dopamine for Hypotension in Extremely Preterm Infants .pdf …

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  5. Caitlin Eason, S. Christopher Derderian review the paper "Eaton S, Ganji N, Thyoka M, Shahroor M, Zani A, Pleasants-Terashita H, Ghazzaoui AE, Sivaraj J, Loukogeorgakis S, De Coppi P, Montedonico S, Sindjic-Antunovic S, Lukac M, Hamill J, Choo CSC, Nah SA, Hulscher J, Emil S, Petersen A, Wijnen R, Sloots C, Sigalet D, Kiely E, Svensson JF, Wester T, Pierro A. STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial. Pediatr Surg Int. 2024 Oct 29;40(1):279. PMID: 39470842." for EBNEO October 2024 Article of the Month. READ HERE! ACTA COMMENTARY: Acta Paediatrica - 2025 - Eason - EBNEO COMMENTARY Stoma or Intestin…

  6. Dyanne Ifeoma Imo-Ivoke, Joanna Preece review the paper "Katheria AC, El Ghormli L, Clark E, Yoder B, Schmölzer GM, Law BHY, et al. Two-Year Outcomes of Umbilical Cord Milking in Nonvigorous Infants: A Secondary Analysis of the MINVI Randomized Clinical Trial. JAMA Netw Open. 2024 Jul 1;7(7):e2416870. doi: 10.1001/jamanetworkopen.2024.16870. PMID: 38949814; PMCID: PMC11217871." for EBNEO. READ HERE! ACTA COMMENTARY: Acta Paediatrica - 2025 - Imo%E2%80%90Ivoke - EBNEO Commentary Two%E2%80%90Year Outcome of Umbilical Cord Milking in Nonvigorous Infants .pdf "Close to term, about a third of the fetal blood volume is within the placenta at any time.(1) At birth, blood flow i…

  7. Anup Katheria & Henry Lee review Knol R. et al's EBNEO December Article of the Month: "Knol R, Brouwer E, van den Akker T, DeKoninck PLJ, Onland W, Vermeulen MJ, de Boode WP, van Kaam AH, Lopriore E, Reiss IKM, Hutten GJ, Prins SA, Mulder EEM, d’Haens EJ, Hulzebos CV, Bouma HA, van Sambeeck SJ, Niemarkt HJ, van der Putten ME, Lebon T, Zonnenberg IA, Nuytemans DH, Willemsen SP, Polglase GR, Steggerda SJ, Hooper SB, Te Pas AB. Physiological versus time based cord clamping in very preterm infants (ABC3): a parallel-group, multicentre, randomised, controlled superiority trial. Lancet Reg Health Eur. 2024 Dec 4;48:101146. doi: 10.1016/j.lanepe.2024.101146. PMID: 39717227; …

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  8. David Rub & Elizabeth Foglia review EBNEO October 2024 Article of the Month: "Gallini F, De Rose DU, Iuliano R, et.al. Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial. JAMA Netw Open. 2024 Sep 3;7(9):e2435347. doi: 10.1001/jamanetworkopen.2024.35347. PMID: 39320892; PMCID: PMC11425149." READ HERE! Discussed on the INCUBATOR PODCAST! ACTA COMMENTARY: Acta Paediatrica - 2025 - Rub - EBNEO Commentary Reassessing INSURE Is Lung Recruitment Necessary.pdf "Few therapies have impacted a field like surfactant has neonatology. Since its discovery in the 1980s, surfactant replacement therapy revo…

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  9. Harisa Spahic, Sandra P. Zoubovsky, & Robert Dietz review EBNEO February 2025 Article of the month: "Faix RG, Laptook AR, Shankaran S, Eggleston B, Chowdhury D, Heyne RJ, et al. Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks’ Gestation: A Randomized Clinical Trial. JAMA Pediatr 2025; e246613. PMID 39992674." READ HERE! ACTA COMMENTARY: Acta Paediatrica - 2025 - Spahic - EBNEO Commentary Is Therapeutic Hypothermia Beneficial to Infants Born Between 33 and.pdf "HIE is a devastating pathology, resulting in significant morbidity and mortality1. TH is the currently the only effective treatment shown to reduce morbidity and mortality i…

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  10. READ HERE! @EBNEO ACTA COMMENTARY: Acta Paediatrica - 2025 - Uguru - EBNEO Commentary Non%E2%80%90Invasive HFOV Versus Nasal CPAP for Preterm Infants.pdf "The management of respiratory distress syndrome (RDS) in preterm infants is a critical aspect of neonatal care, and the choice of non-invasive ventilation strategies can significantly impact clinical outcomes. Among the various modalities available, Non-invasive High-Frequency Oscillatory Ventilation (NHFOV) and Nasal Continuous Positive Airway Pressure (NCPAP) have garnered attention for their roles in supporting preterm infants with varying degrees of RDS. Both techniques, each with distinct mechanisms and clinical …

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