Alex Posted August 6, 2014 Share Posted August 6, 2014 Dear colleagues, do you have experience with surfactant treatment in innate and nosocomial pneumonia? Many thanks for attention. Link to comment Share on other sites More sharing options...
Francesco Cardona Posted August 6, 2014 Share Posted August 6, 2014 Interesting idea. We have on individual occasions given surfactant to our patients, mostly without any significant respiratory improvement. Surfactant levels seem to be reduced in pneumonia http://www.atsjournals.org/doi/abs/10.1164/ajrccm.153.1.8542113#.U-I7bGNBl14 There seems to be some recent research on this issue though: in mice: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.1996.tb05580.x/abstract possibly it is another phospholipid that is disrupting the function of surfactant during pneumonia: http://www.ncbi.nlm.nih.gov/pubmed/?term=20852622 Link to comment Share on other sites More sharing options...
selvanr4 Posted August 11, 2014 Share Posted August 11, 2014 good thoughtful links thanks Link to comment Share on other sites More sharing options...
nashwa Posted August 12, 2014 Share Posted August 12, 2014 Fcardona....I understanded from your topic that you not recommend given surfactant in pneumonia. Link to comment Share on other sites More sharing options...
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