Posted August 6, 201410 yr Dear colleagues, do you have experience with surfactant treatment in innate and nosocomial pneumonia? Many thanks for attention.
August 6, 201410 yr Interesting idea. We have on individual occasions given surfactant to our patients, mostly without any significant respiratory improvement. Surfactant levels seem to be reduced in pneumonia http://www.atsjournals.org/doi/abs/10.1164/ajrccm.153.1.8542113#.U-I7bGNBl14 There seems to be some recent research on this issue though: in mice: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.1996.tb05580.x/abstract possibly it is another phospholipid that is disrupting the function of surfactant during pneumonia: http://www.ncbi.nlm.nih.gov/pubmed/?term=20852622
August 12, 201410 yr Fcardona....I understanded from your topic that you not recommend given surfactant in pneumonia.
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