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surfactant treatment in pneumonia?

Alex
in Respiratory Disorders

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Dear colleagues, do you have experience with surfactant treatment in innate and nosocomial pneumonia? Many thanks for attention.

Interesting idea. We have on individual occasions given surfactant to our patients, mostly without any significant respiratory improvement.

Surfactant levels seem to be reduced in pneumonia http://www.atsjournals.org/doi/abs/10.1164/ajrccm.153.1.8542113#.U-I7bGNBl14

There seems to be some recent research on this issue though:

in mice: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.1996.tb05580.x/abstract

possibly it is another phospholipid that is disrupting the function of surfactant during pneumonia: http://www.ncbi.nlm.nih.gov/pubmed/?term=20852622

Fcardona....I understanded from your topic that you not recommend given surfactant in pneumonia.

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