selvanr4 Posted October 21, 2009 Share Posted October 21, 2009 we had 2 newborns prentong with culture proven staph sepsis. they had colour change to black pigmentation while on drugs. any strain which causes colour change? Link to comment Share on other sites More sharing options...
JACK Posted October 21, 2009 Share Posted October 21, 2009 Could it be due to the drug used ? Which antibiotic was used in these cases ? Link to comment Share on other sites More sharing options...
selvanr4 Posted October 22, 2009 Author Share Posted October 22, 2009 both the babies received inj. amikacin and piperacillin &tazobactum. they have received platelet transfusions also selvan Link to comment Share on other sites More sharing options...
Stefan Johansson Posted October 22, 2009 Share Posted October 22, 2009 Looks like the infant developed a pustular rash. How about this condition? "Acute Generalized Exanthematous Pustulosis: A Rare Clinical Entity With Use of Piperacillin/Tazobactam." http://www.ncbi.nlm.nih.gov/pubmed/19352142 Link to comment Share on other sites More sharing options...
selvanr4 Posted October 23, 2009 Author Share Posted October 23, 2009 i agree to the pustular rash on the foot. But the black colour change on the face, nape of neck are out of blue. i will search again and come back to you with the latest pictures next week when they come back fo review from the primary care practitioner. Link to comment Share on other sites More sharing options...
Guest Dukstar Posted October 24, 2009 Share Posted October 24, 2009 I saw these slate-like coloration in neonatal chikungunya infection Was there an epidemic of chikungunya at this period in your setting ? Link to comment Share on other sites More sharing options...
JACK Posted October 24, 2009 Share Posted October 24, 2009 Was any lotion applied locally ? Any herbal medicines ? Link to comment Share on other sites More sharing options...
selvanr4 Posted October 25, 2009 Author Share Posted October 25, 2009 we have chikungunya infection as epidemic right now with dengue . no lotion was applied . i am posting other photos selvan.r. india Link to comment Share on other sites More sharing options...
Guest Dukstar Posted October 27, 2009 Share Posted October 27, 2009 It seems that the hyperpigmentation interest periorificial sites and lobes of the ears. You can screen for CHIKV infection (perhaps IgM if too late for RT-PCR), specially if these newborns have been febrile... Maternal-fetal transmission has been described with febrile mothers during the peripartum period with onset of disease in neonates after some days. See my publication here : http://www.ncbi.nlm.nih.gov/pubmed/17721376?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Link to comment Share on other sites More sharing options...
selvanr4 Posted October 27, 2009 Author Share Posted October 27, 2009 thanks a lot for the information. indeed i could get more information after seeing your article. both the babies are well and thriving and now in their homes. thanks selvan.r Link to comment Share on other sites More sharing options...
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