selvanr4 Posted May 10, 2019 Share Posted May 10, 2019 I have seen 2 newborns recently with hyperinsulinemic hypoglycemia. Both of them settled down with diazoxide.How common is the transient form? 1 Link to comment Share on other sites More sharing options...
Dr Khalil Ahmad Posted May 14, 2019 Share Posted May 14, 2019 we do see these cases, and usually they respond in a week or 10 days time. difficult to say how common but its not very uncommon too. 1 1 Link to comment Share on other sites More sharing options...
Stefan Johansson Posted May 14, 2019 Share Posted May 14, 2019 We also come across infants that clearly have slightly elevated s-insulin (with low blood sugars) despite hypoglycemia. My limited experience is - diazoxide has worked very well and we have been succesfully withdrawing diazoxide before discharge (like after a week or so). 1 1 Link to comment Share on other sites More sharing options...
Dr Jubara Alallah Posted May 20, 2019 Share Posted May 20, 2019 We come across infants that have e hyperinsulinemic hypoglycemia, few are transit responded to diazoxide the rest turn to be Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) they have Mutations of SUR1. and 2 cases with Donohue syndrome (severe insulin resistance, hyperinsulinemia postprandial hyperglycemia, preprandial-hypoglycemia. 2 1 Link to comment Share on other sites More sharing options...
M C Fadous Khalife Posted May 21, 2019 Share Posted May 21, 2019 This is not common; in 5 years just saw 2 cases; effectively good response to diazoxide 2 1 Link to comment Share on other sites More sharing options...
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