Dear All,
 
	I would like to seek your help. I remember I read about differences between Fentanyl and Morphine action during cooling protocol in our NICU patients. Unfortunately, I cannot find the evidence now (may be I am looking wrong) whether Fentanyl or Morphine is better option. Both are metabolised slower during cooling and we have to be careful in administration. My knowledge is that Morphine was drug of choice due to better binding to pain receptors and a bit better action during cooling. I remember some article (from Pediatrics, Neoreview?) and there was mentioned even some protective effect of Morphine. Can you help me with sources or whether it is still true? I know that now Clonidine is being studied as possible neuroprotective drug too but nothing specific about mentioned  meds above.
 
	Thank you very much
 
	Zuzana