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If you work in Neonatology you no doubt have listened to people talk in rounds or at other educational sessions about the importance of opening the lung. Many units in the past were what you might call “peepaphobic” but over time and with improvements in technology many centers are adopting an attitude that you use enough PEEP to open the lung. There are some caveats to this of course such as there being upper limits to what units are comfortable and not just relying on PEEP but adding in surfactant when necessary to improve pulmonary compliance. When we think about giving nitric oxide
I am currently writing my dissertation on the use of non-invasive ventilation to deliver nitric oxide in neonates and I was wondering: What are people‘s experiences of using non-invasive iNO with CPAP, Nasal cannula, oxygen hood etc? Which gestational have you primarily used it with? What were the indications/ underlying pathologies? Have you found this has reduced the need for mechanical ventilation or ECMO? Have you needed to deliver higher doses to achieve the same effect seen on mechanical ventilation? Which countries
Just wanted to share a recent and good experience with inhalation of epoprostenol in PPHN. I currently work in a large level2-unit (≈8000 inborn/y) with no access to NO-inhalation. Infants born in our delivery ward with PPHN and needing level-3-care (i.e. NO/mechanical ventilation) needs to be transferred. We recently had a baby with echo-verified PPHN, on CPAP and with saturations around 88-90% on 100% oxygen. While preparing for premed/relaxation and intubation we connected our CPAP inhalation device and inhaled epoprostenol with surprisingly good response! We avoided intubation and