Check out this great lecture by @Nathan Sundgren about recent advances in neonatal resuscitation, i.e. sustained inflation and minimal-invasive surfactant therapy.

 

 

Thanks for sharing.

Time stamps

00:24- objectives 

00:50 - disclosures

1:20 - SLI demonstration

1:38 - Meta analysis 2015 : SLI vs PPV : No diff in death and BPD

2:10 - SAIL trial: stopped early due to more deaths < 48 hrs. No diff in death and BPD.(80% infants completed the trial)

2:42 - Schmozler 2018 : Feasibility RCT done , results in favour of CC+ SI 

3:04 - Cochrane : surfactant benefits

3:44 - Isayama T: network meta-analysis 2016

5:43 - LISA technique

6:12 - AMV trial by Gopel: LISA reduced MV

7: 28 - Isayama: excluded AMV from network meta analysis: reason explained

7:39 - OPTIMIST: ongoing trial: extreme preterm

7:44 - NINSAPP trial: < 26 week .. Air leak less in LISA

9:22 - LISA vs INSURE: No diff for BPD

10:04 - SURE vs INSURE : less MV(primary outcome) and BPD(secondary outcome): larger infants included, no subgroup analysis

12: 14 - NRN Review

13:14 - Probable formulated protocol

Thank you.

A big thanks for sharing. I hope it is helpful to many of you. Follow the You Tube channel - TexSun NeoEd - if you like it. You never know when I might put something else up.

17 hours ago, Nathan Sundgren said:

A big thanks for sharing. I hope it is helpful to many of you. Follow the You Tube channel - TexSun NeoEd - if you like it. You never know when I might put something else up.

@all - here is the URL: https://www.youtube.com/channel/UC3g3Gs_HiffehrdWiivKReg

@Nathan Sundgren - also consider to share your videos directly here too, just start a topic in a forum, write a sentence or two and copy/paste the Youtube URL and it will embed automatically

Thank you for sharing 

Check this out in JAMA Ped, systematic review on ”Sustained Inflation vs Standard Resuscitation for Preterm Infants  - A Systematic Review and Meta-analysis”

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2760413?guestAccessKey=b2009b9d-ddfc-478a-b681-14a83387dc94&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamapediatrics&utm_content=olf&utm_term=020320