Neurological Disorders

Read an interesting news article LINK Any comments? Some related reading Cilio MR, Ferriero DM. Synergistic neuroprotective therapies with hypothermia. Semin Fetal Neonatal Med. 2010 Mar 6. [Epub ahead of print] PubMed PMID: 20207600. LINK Cattano D, Williamson P, Fukui K, Avidan M, Evers AS, Olney JW, Young C. Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain. Can J Anaesth. 2008 Jul;55(7):429-36. PubMed PMID: 18591700. LINK TO DOWNLOAD Ma D, Hossain M, Chow A, Arshad M, Battson RM, Sanders RD, Mehmet H, Edwards AD, Franks NP, Maze M. Xenon and hypothermia combine to provide neuroprotect…

Is anyone trying hypothermia, systemic or cranial, to minimize the effects of HIE? Candidates for this form of therapy must first be placed on aEEG to determine if any brain activity is present. Sustained cranial or systemic hypothermia needs to be initiated by 6 hours from birth to be effective.

Does anyone have experience in using Keppra/Levetiracetam in neonatal seizures ?

Dear All, Please enlighten me on how to come to a conclusion on following CSF report 30 weeker, LP done on day 3 of starting antibiotics prophylactically for prematurity. Only indication was to do a LP was positive blood culture for Group B strep and high CRP. Infant didn't have signs of Meningitis. CSF report- RBC 15/mm3 WBC 7/mm3 (Neutrophils 3, Lymphocytes 4) Protein 40mg/dl CSF sugar 65mg/dl RBS 75mg/dl CSF Antigen/culture both Negative My concern mostly is 3 neutrophils, Would you consider this LP as positive and please comment on normal differential counts of WBC in premature/Term neonates. Many Thanks!

I would like to know the appropriate age for doing OAE in neonates for hearing screening. We have recently started cheking neonates in nicu and normal neonates in postnatal wards for hearing by oae.The person who checks fpr oae will do for all neonates in nsy irrespective of age, as early as 6 hrs of age. I have noted that at age <24 hours more reports are interpreted as refer than when done later. I came to know that right age for normal vaginal births is >24hrs nd cesarian births>48 hrs of age. What is the practice at other units and what is the most suitable time for doing oae

Baby I was admitted 2 days back with h/o secondary apnoea after LSCS for oligohydramnios. Mother had UTI in the last week of pregnancy.Baby needed intubation and he was transferred here.On arrival he had frank seizure. His sugar calcium normal. He had normal PT and normal range aptt( 40 sec) and low platelets. He was ventilated and investigated. I am attaching the CT scan pictures. He is on phenobarb, phenytoin , midazolam and levitracetam. He is seizure free for the last 24 hrs. His repeat CT shows almost same lesions which are more prominent. Please share your views on the longterm outcome of the baby? dr.selvan rathinasamy Erode. India

Can the term "Perinatal Asphyxia" be used interchangeably with "Birth Asphyxia"? or Is the term Birth Asphyxia is OUTDATED?

Do you routinely screen your NICU graduates for hearing? At what age do you do so? Who are the candidates for such screening? In case of abnormal screen what is your action plan? Could you kindly share your views.

We sometimes end up having a baby who has had HIE , now presenting with obvious delayed developement. The concept of early stimulation is well known We have not had practical experience in treating these children. I know the various institutions which claim absolute recovery. If a member of 99 nicu has had the experience please share with us your knowledge.

Much has been said that midazolam may hinder the growth of premature brains. On this basis, is it correct to prohibit the use of midazolam in the NICU? Any articles on pros and cons of its use.