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Do you use caffeine (citrate) at a dose of >20 mg/kg and do you follow serum levels?

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20 hours ago, Stefan Johansson said:

We posted a short survey on Twitter about dosing of caffeine.

  • Do you use caffeine (citrate) at a maintance dose of ≥20 mg/kg/day?
  • Do you follow serum levels of caffeine?

Take the survey on Twitter and/or share your practises here!

 

 

We do not use caffeine (citrate) at a maintance dose of ≥20 mg/kg/day. In our NICU, we can not  monitor serum levels of caffeine.

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We use Coffein citrat 》 20 mg/ ml po/IV for some special individual cases. And we monitor Caffeine Levels, jitterness, tachycardia. We find no close correlation between caf. Levels and high doses.  We succed in prevention of intubation most ofen in using doxaprame hydrochlorid.  

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  • 2 weeks later...

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Vicky, Interesting point: We use caffeine citrat once a Day (makes sense pharmacologically): on the other side: sometimes we See more Apnea at the and of a 24 hour period. Then we change to twice a Day.

But sometimes we stop caffeine at 34 weeks post conc. and recognize apnea appearing again after 36-48 hours. So there mich be an Individual or biochronical diversity.

Mich = Might 

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We use caffeine citrate 5 mg/kg once a day for maintenance. Very rarely, we need to use up to 10-12 mg/kg/d and old use twice a day schedule if still needed at term (extremely rare)

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We use caffeine citrate 5 mg/kg once a day for maintenance. We monitor caffeine serum levels before increasing maintenance dose in case or persistent recurrent apneas.

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