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Budesonide Nebs No, Yes (if so When)?


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Hi 99ers,

Do you regularly use Budesonide nebs in the preterm population? If so what guides your use  ( FiO2, mode of support, CXR changes ) and if so what is the length of the course (days or weeks). Not sure the evidence is there but it is becoming more prevalent.

Thanks, have a good weekend 👍

Ali

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Not regularly any longer. (I am also non-believer :) after the Neurosis trial)

But sometimes, someone (not me!) starts inhalations, I'd say typically at ~32 weeks post-conceptionally if BPD-development is more complicated ("higher" FiO2 [I'd say >50% and increasing] and "higher" CPAP-pressure dependency). We have guideline about this though.

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We use it regularly starting around 27wks cga or at 2 weeks of life to help facilitate weaning. We start at 0.25mg BID and increase to 0.5mg if needed. We have wonderful BPD rates. We use this along with Diruil- we haven’t trached for BPD in many many years! 

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