Cardiovascular Problems

hello, we have noticed that when phototherapy is used on day 3-4, we get PDA opening and new murmur. Any coincidence? have you come across this ? selvan.r.dr ERODE,INDIA

I am interested in pulse oxymetri screening, but we do not perform such screening in our maternity units. Yesterday, a Swedish group published in BMJ, a large screening study including almost 40.000 infants. It seems that the article is available in free full text format here! My question to you is... since this method has been discussed for a pretty long time now - do you already now perform pulse oxymetri screening before routine discharge of well babies? If yes, what is your experience?

how does Indomethacin & like drugs close PDA in the neonatal period? And why the same drugs do not act later? thanks selvan.r

Hello, colleagues! I have a question about therapy of PDA. We are not very experienced in drug therapy for PDA. Sometimes we can use ibu for it. And I wonder: if after the first course the duct remains open, but not significant (for ex. less than 1 mm, no murmur, no clinic), should we continue a therapy (the second course) or not? Thank you

Hi everybody,is there any role for sildenafil in pphn

When using inotropics in PPHN many guidelines advocate the primary use off dopamine up from 5-15 (20) μg/kg/min and if that fails the add on of dobutamine. While it makes perfect sense for me to start with dopamine I fail to understand the argument for dobutamine. It is almost exclusively a β1 active sympathomimetic with very little, if any, effect on α receptors and on blood pressure. That makes it very attractive in the setting of cardiac failure, where one wishes to increase the contractility of the heart with out burdening the strained pump with an increased after load. Its use in PPHN however, where you presumably have a normally functioning myocardium and p…

Just wanted to know if anyone has any experience in using reteplase for fibrinolysis in neonates.

Antithrombotic therapy in neonates and children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Monagle P, Chalmers E, Chan A, DeVeber G, Kirkham F, Massicotte P, Michelson AD; American College of Chest Physicians. Chest. 2008 Jun;133(6 Suppl):887S-968S. LINK

Hi everybody,how do you manage PPHN

Dear colleagues, a cordial greeting. I would like to know if somebody has experience using it pulse pressure variation (∆PP) in patients with acute respiratory distress syndrome to monitor a newborn in mechanic ventilation. Sincerely, Fernando Agama C. Hospital "Dr. Enrique Garcés" Quito-Ecuador