Cardiovascular Problems

i want to know about the use of indomethacine vrs iboprufen on PDA treatment

dear collegues, Some times we recieve neonates with severe hypoxemic failure due to various causes without infection and with intractable shock due to PPHN despite central venous cath., dopamine (20ug/kg/mn), dobutamine (20-30 ug/kg/mn), 4-6 fluids boluses of 10-20ml/kg, inhaled NO, sedation and effective mechanical ventilation. echocardiography shows frequently signs of PPHN. the question that i would like to answer is that what should we use after: epinephrine, norepinephrine or other thing?

If you're particularly interested in the patent ductus arteriosus, you may be interested to visit the web site PDA.SE Besides a reference library, clinical protocols and a video clip library (work in progress...) there's also a section for parents, with a information leaflet for parents. The leaflet is available in Nordic languages and English, and translations in other european languages is on the way.