Aedi Budi Dharma Posted April 14 Share Posted April 14 Greetings to all.. We have some issues that need clarification, at least in neonatology perspective. 1. what is the minimal platelet count for surgery (e.g abdominal surgery) in preterm infant? 2. Do you routinely measure coagulation test before surgery? Especially in preterm infant? 3. Do we have evidence for this? Thank you for your kind attention 1 Link to comment Share on other sites More sharing options...
Stefan Johansson Posted April 16 Share Posted April 16 Hi there! The Stockholm practises (no written guidelines) are 1. ~100-ish 2. Depends, but if major surgery (like NEC) this is usually done as part of the workup 3. Not that I am aware of 1 1 Link to comment Share on other sites More sharing options...
rehman_naveed Posted April 16 Share Posted April 16 Yes we always measure. Just asking you a question that supposed these were not done and on table baby die due to bleeding, who to be blamed? Pre planned investigation and blood products arrangements are necessary. Not everything is evidence based, some common sense is also must. I hope this helps. regards 1 1 Link to comment Share on other sites More sharing options...
APiotrowski Posted April 16 Share Posted April 16 Yes we measure APTT, Platelets, Fibrinogen. Minimal value for platelets would be 100 000 per ml. Greetings ! 1 1 Link to comment Share on other sites More sharing options...
aalnemriksu Posted April 16 Share Posted April 16 We routinely check platelets and coagulation profiles for preterm infants We do not feel comfortable to send baby to OR with platelets less than 100 1 1 Link to comment Share on other sites More sharing options...
Mo7 Posted April 18 Share Posted April 18 Interesting topic, but I check this case report we published 🙂 https://pubmed.ncbi.nlm.nih.gov/30413439/ 1 1 Link to comment Share on other sites More sharing options...
M C Fadous Khalife Posted April 21 Share Posted April 21 1- A platelet count of at least 100,000 per microliter is recommended. 50000 for minor interventions 2- Yes we measure 3- Yes done by the American Societies of Anesthesiology and American Society of Hematology and there is a recent article from 2020 published in the Lancet Hematology for immune hematology cases tolerating surgery at less than 50000 platelets count anyway this must be evaluated case by case 2 Link to comment Share on other sites More sharing options...
piatkat Posted May 5 Share Posted May 5 Hi, I found this one paper: Platelet Transfusions in the Neonatal Intensive Care Unit https://www.sciencedirect.com/science/article/pii/S0095510815000391?via%3Dihub they address also requirements before surgery, but they acknowledge lacking data for preterm infants. The paper is from 2015. While looking for something newer, I created a ResearchRabbit network of papers, you can check it out here: https://www.researchrabbitapp.com/collection/public/0LJWEY98ZW When you click "Later work", it will display papers which are connected with the papers mentioned in this thread Maybe you will find something interesting. Good luck! Link to comment Share on other sites More sharing options...
Dr Jubara Alallah Posted May 5 Share Posted May 5 The minimal platelet count required for surgery in preterm infants varies depending on the individual infant's clinical status and the type of surgery planned. In general, a platelet count of at least 100,000/mm3 is considered safe for most surgical procedures in preterm infants. ( this is our practice in our institute ) However, it is important to note that the decision to proceed with surgery should be made on a case-by-case basis, taking into account the infant's clinical status, coagulation profile, and the risks and benefits of the procedure. Additionally, other factors such as the infant's gestational age, birth weight, and comorbidities may also impact the decision-making process Link to comment Share on other sites More sharing options...
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