Respiratory Disorders

Hi there, T/SGA with perinatal asphyxia/DIC/pneumothorax/mas/ sepsis-clinically improving-activity better, no bleeds, pneumo resolved, on SIMV(1:1 vent)-13/4/23(rate) /25%-latest abg-7.6/21/102/22.Respiratory efforts are poor/ ocassional. No sedation, phenobarbitone also stopped . Responds to physical stimuli with respiration going >60. what ventilatory changes do you suggest.

How do you differentiate PIE vs. early cystic BPD? A former 25week preemie developed cystic lung lesions as evidence of chest x-rays at 2weeks of age. The infant was born through maternal chorio, no NAS given, developed RDS, required two doses of survanta and antibiotics started for suspected sepsis, completed 7 days. Initial Hct was 19, infant received multiple PRBS transfusions, but developed pressor-resistant hypotension requiring Dopa/Dobutamine/Epinephrine/Hydrocortisone. A left grade 4 IVH and right grade IVH was noted on DOL2, stable on follow ups. Pt remained on CMV, moderate settings until DOL7 that was switched to HFOC due to requiring significant peak pressure…

Dear colleagues I'd like to know if anyone uses Respironics NM3 monitor, and how reliable it is in premies < 1000g. Your feedback will be highly appreciated.

Kind regards to all. In the NICU of our hospital in the city of Quito, we hospitalized 72 days for a girl who have diagnosed a Congenital Central Hypoventilation Syndrome (‘Ondine’s curse). Almost every day of his life has been connected to a mechanical ventilator. We want to know if anyone has any suggestions as to its management. Sincerely, Fernando Agama C. Unidad de Neonatología Hospital "Dr. Enrique Garcés" Quito-Ecuador

Check this out, from todays issue of NEJM! Clinical research at its best! Caffeine Therapy for Apnea of Prematurity, Barbara Schmidt et al Editorial comment by Eduardo Bancalari Caffeine as BPD treatment!? I think this finding was a bit surprising for the research group, given that authors stress the possibility of a potential harmful effect of xantines in the Intro of the paper. I think the (ongoing) follow-up studies will be of great interest, I hope they'll publish results soon.

Dear Colleagues!!! Please, share with me your experience with Infasurf as surfactant replacement therapy in RDS. Still now, we are using Curosurf for this purpose. Probabaly, some of you used both these surfactants. I would like know to what is better as medicine of choice. Leonid

Dear Colleagues, Has anyone recently been into revised clinical strategies related to reduction of BPD in VLBW/ELBW babies in your institution? If so I would like to know more about it and happy to share some of the thoughts. We are planning to revise our management lines. Grateful if you could also share your new plans. Thanks. Dr S Chandran Singapore

Now we are writting the guide for the bronhopulmonary displasia and there are discussion about the terminology: BPD or pulmonary chronic lung diseases. Which term is correct?

we have had 2 newborns one recently and another one 9 yrs back. Both of them were delivered vaginally with no antenatal steroids . Both of them didn't need any ventilatory support. Had normal x rays. Aminophylline given prophylactically. Didn't need PPN or TPN. Slowly adapted to EBM. Now doing well. What helped these babies to have normal surfactant production in view of normal x rays? I am eager to know your reasoning for this phenomena.

Hi everybody I want to ask if there is an optimal or cutoff level of FiO2 after which I can remove nasal cpap to headbox or incubator O2 . afaf korraa prof of pediatrics and neonatology