Respiratory Disorders

Would anyone be willing to share their evidence based protocol or guideline for the Infant Flow SiPAP? Owen's 2008 survey of UK NICU's use showed that 36% of those that responded used SiPAP. I have looked at the available evidence, but I also need to review existing protocols/guidelines. Given the relatively small amount of evidence, it may be fair and reasonable to include information on the "who, when and how" from other NICU's who have had more experience with SiPAP. If you are interested and can help, please email me andrew.shearman@mater.org.au Thank you.

Does anyone use Pulmozyme in their NICU in patients with atelectasis? Thanks, Beau

Please read this article and then answer my questrions: Should we administer antenatal steroids to mothers preganat 34-37 weeks planned for elective CS? Bastek JA, Sammel MD, Paré E, Srinivas SK, Posencheg MA, Elovitz MA. Adverse neonatal outcomes: examining the risks between preterm, late preterm, and term infants. Am J Obstet Gynecol. 2008 Oct;199(4):367.e1-8.

Dear 99nicu friends Please give your comments on this pioneer study. J Pediatr. 2008 Jun 3. [Epub ahead of print] A Randomized Controlled Trial of Theophylline Versus CO(2) Inhalation for Treating Apnea of Prematurity. Al-Saif S, Alvaro R, Manfreda J, Kwiatkowski K, Cates D, Qurashi M, Rigatto H. Departments of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada. OBJECTIVE: To determine whether inhalation of 0.8% CO(2) in preterm infants decreases the duration and rate of apnea as effectively as or better than theophylline with fewer adverse side effects. STUDY DESIGN: A prospective, randomized, control study of 42 preterm infants of gestati…

It's not the first time we have isolated P. Aeruginosa from pulmonary mucus in intubated preterms. Everytime we have this germ, we asked ourselves the same question: Is there enough evidence to treat with antibiotics to this preterm babies with a cronic lung disease, if there isn't a bloodstream infection and the child evolution is good?

A series of articles published recently have indicated the danger of nCPAP on our premies' ears Surenthiran SS. Arch. Dis. Child. Fetal Neonatal Ed. 2003;88;315-318 Karam O. Arch. Dis. Child. Fetal Neonatal Ed. 2008;93;F132-F134 Trevisanuto D et al. Arch. Dis. Child. Fetal Neonatal Ed. 2008;93;F396-F397

A new article is going to be released soon on facial nerve palsy as a complication of flow driver CPAP in ELBW infants by Maffei G, et al. J Perinat Med 36 (2008). Did experinece this complication in your practice?

The very concept of aerozolized sufactant sounds very interesting. I went through this and found it promising. Donn SM, Sinha SK.Aerosolized lucinactant: a potential alternative to intratracheal surfactant replacement therapy. Expert Opin Pharmacother. 2008 Feb;9(3):475-8. Review. LINK

Dear Colleages, especially in Sweden, I would like to know if you use INSURE technique (intubation, surfactant, extubation) for babies around 27-28 wks GA (# 1 kg) whose mothers are unbooked and didi not receive antenatal steroids. Best Regards

what is the latest trial of steroid course in chronic lung disease?