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Hematological Conditions

  1. Started by JACK,

    Just wanted to inform the members, that the 9th edition of "Antithrombotic Therapy in Neonates and Children: Antithrombotic Therapy and Prevention of Thrombosis" from American College of Chest Physicians is out. Link

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  2. Dear colleagues! I meet a cases with different hemorrhage locations (4 intracranial, 1 in adrenal hematomas in both glands). All stories communicated with low-molecular- weight heparin use in pregnancy. Some later I sow in literature a case about subdural intrauterine hematoma of fetus associated with low-molecular- weight heparin use. Do you have information about complications in newborns after heparin administration in pregnancy? Thanks to you. Alex.

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  3. Hi, I recently heard of a case of an infant born at term from an apparently uncomplicated pregnancy. Mother of the infant with h/o sickle cell trait. Mother visited the OB doctor at 40 weeks due to painful contractions. Questionable decreased fetal movements was recollected on further questioning, but no clear on initial presentation. Mother was admitted to L&D due to active labor. A stat c-section was performed after 4hrs of labor due to a category III fetal heart tracing (with absence of variality). A severely depressed infant was born through meconium-stained amniotic fluid. ET intubation was performed, but no mec was seen below the glottis. PPV was initiated due…

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  4. Started by m.jahanshahifard,

    Thrombocytopenia: Neonatal Alloimmune (Isoimmune) severe, with platelet counts often ≤10,000/μL in the first day of life. The maternal platelet count is normal increase risk for intracranial hemorrhage, both prenatally and postnatally. diagnosis: clinical The treatment: transfusion of washed irradiated maternal platelets. Irradiated, random-donor platelet if active bleeding & maternal platelets are not immediately available. Intravenous γ-globulin (1 g/kg daily for 2 days) or corticosteroids ( methylprednisolone 2 mg/kg per day), or both Elective cesarean section has been advocated for infants at risk Thrombocytopenia Result…

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  5. One of our term newborn presented thrombocytopenia (with antibodies maternal IgG) and neutropenia (with maternal HLA antibodies), hours after transfusion of platelets and Ig Vena and Neupogen is better. Has anyone had any cases in which thrombocytopenia is associated with neutropenia? parents are South Americans. Thanks.

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  6. A 29 2/7 weeks male infant was born two days ago from a 25 y/o G1P0 healthy pregnant mom. MOC showed up in preterm labor, with PPROM, and infant was born by CS due to NRFHT. Apgars 2 and 8. Infant intubated at delivery, given curosurf and weaned from the vent over 6hours. Tolerated HFNC at 5 lpm, on 20's FiO2. Amp and Gent started for suspected sepsis. Maternal serology was negative, (HIV, RPR, GBS). No maternal chorio. A CBC at 24 HOL showed WBC in the 65k, with 19% Bands, 11% myelos, 7% meta. Baby otherwise clinically stable. No phenotypic features of down syndrome. 1- What causes this phenomenum? 2- How log does it ussually last? 30 any reference article of idipatht…

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  7. Started by ali,

    Hello Everyone, I am intrigued to learn what your views are on determining whether reticulocyte counts have a bearing on your decision to transfuse or not, and whether or not you have a set guideline. Thanks Alistair

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  8. In your opinion what is the safe HB at which to send the newborn home ?. This question arose because we had few newborn who had persistently low HB since birth. We try to keep the haemotocrit to above 45 in sick newborns. Does the same applies here? dr.r.selvan Erode, India

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  9. We had a neonate born to rh negative mother. Baby developed hyperbilirubinemia. needed 2 exchange transfusions and 3 top up packed cell transfusions. We send the baby at 13.9 gm%. Has returned back on day 30 with HB of 5 gms%..Now we needed to give packed cells. Our fetal medicine consultant says that she has seen this happen frequently when the final HB is high. She feels that the hypoxic drive for erythropoitin is gone and hence the lavel is low. Marrow sleeps off. Her advice is to keep HB around 10 gms%. Give me your feedback? dr.r.selvan Erode, India

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  10. National Institute for Health and Clinical Excellence (NICE) in the UK has published guidelines on how to manage neonatal jaundice. The guidelines provide guidance on the recognition, assessment and treatment of neonatal jaundice in term and preterm infants from birth to 28 days. A series of documents are published at http://www.nice.org.uk/guidance/CG98 In the full guidance document, there are treatment threshold graphs for infants born from 23 gestational weeks and onwards.

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