Medication & Pharmacology

Hi everyone, I am intrigued as to whether other units preferentially use an oral or iv preparation when attempting to wean ventilator dependent infants. Our oral preps result in such small doses as the regime tails off I am now concerned that even the smallest vomit/posset/aspirate could inhibit the efficacy of outcome. Would it be more pragmatic to curtail administration to purely iv. Value any thoughts. Best wishes Alistair

Good evening all, I have a keen interest in aerosol delivery to neonates and am trying to characterise the levels of aerosol deposition in these children's lungs. As you may know, there are not too many in vivo studies characterising aerosol deposition in this population and so I need to rely on preclinical and in vitro work. Over the last number of months, I have been trying to source CT scans of preterm (ELBW, LBW) neonates with a mind to creating a cast model using a rapid prototype machine, similar to The Sophia Anatomical Infant Nose-Throat (Saint) model (9 mth old). Unfortunately, I have found these CT scans are hard to source. I am reaching out to the …

Hi everyone, Our unit drug compatibility chart is well over ten years old. Does anyone know of any sites or links with regard drug comptibilities in neonates. Thanks Al

Is there any value in a third or fourth course of steroids to assist in ventilator dependency. Would value thoughts/opinions. Kind regards Alistair

Do you have any expierence with paracetamol for analgesia in preterm infants, especially after surgery? Which dosis and how often do you administer?

I am looking for some advice regarding treatment for chylous ascites. Term baby delivered at 3.5 kg . Fetal ascites noted by obstetrician also on antenatal scan. Clinically well , no edema, no evidence of hydrops etc. Now 2 weeks old with no respiratory compromise. Not a lot in the literature. Thanks

Dear colleagues on the list Previously we posted a request concerning national guidelines about neonatal pain, and recieved some good information. Thanks a lot! The results will be compiled in a scientfic report. Many of these guidelines give recommendations on a general level but no details about drugs or doses. We would therefore try to get som example from clinical practice over the world and have thus constructed a short web-survey about premedication before intubation of neonates. We are aware that this is not a scientic data collection but also voluntary answers given on an internet resource can give a snapshot of the actual situation. We kindly ask all …

Dear fellow-members! Together with a student, Isa Sundell, I try to collect national guidelines for neonatal pain management. With helpful support from many professionals in neonatology worldwide, we have received several examples, and have compiled a list of the result so far (see short list below). I now turn to you: maybe there are new guideIines or updates we are not aware of. It would be a great help to us if you could send information about such guidelines in your country. Absolutely best would be to recieve an electronic copy or a web-link, or in printed form to adress below, but second best would be a reply to the following questions: 1 Country: 2 Year o…

Dear Colleagues, what is your experience about the efficacy of oral agar as a treatment of Neonatal Jaundice, is there any updated data about this issue thanks

Dear Colleagues, I am an adult neurologist and actually consult one of my myasthenic patients and her newborn with the department of gynecology and our perinatal intensive care unit. The mother is free of symptoms, she is on Mestion five times /day. The newborn has a neontal (transient) myasthenia. She is 3,5 kg, 52 cm. Fortunately she does not have severe atonic generalised weakness but has bulbar symptoms. No problem with the swallowing at rest, but crying and sucking is week and she has relatively early fatigue when she is on breast. She has a good reaction for pyridostigmine but the main problem is the drug supply. When we give the drug before the breast …