Medication & Pharmacology

Dear 99ers, I would be interested (perhaps even worthy of a Poll) to find out if when an infant is on the DART regime whether clinicians lengthen or tailor the course of Dexamethasone (a longer tail so to speak), and what influences that decision (ie a 2nd course, X ray changes, FiO2). Thank you for your thoughts and opinions. Take care, and fingers crossed for COP26. We are all working hard to improve the outcomes for the coming generation - let’s hope they display a similar commitment 🤞 Best wishes Al

We posted a short survey on Twitter about dosing of caffeine. Do you use caffeine (citrate) at a maintance dose of ≥20 mg/kg/day? Do you follow serum levels of caffeine? Take the survey on Twitter and/or share your practises here!

Good morning 99ers, I would be extremely grateful if anyone has experience or a protocol on the use of anakimra in neonates. Thank you Al

Hi I want to know any article or evidence to know that drugs which were contraindicated through picc line. Apart from blood product. Thanks

Dear Colleague, I am a hungarian neonatologist, made a questionnaire about neonatal pain. The aim of this questionnaire is to explore pediatricians' knowledge and practice of neonatal pain in different countries across Europe. Could you please help me by filling this questionnaire. To reach as many pediatrician residents, trainees, fellows, consultants as possible I would appreciate if you could forward or circulate the survey within your Department. Filling out the questionnaire is anonymous, voluntary and will take about 10-15 minutes. The collected information will only be used for this purpose.The data will be stored on a secured server that is acces…

I like to share this article about neonatal pain management I consider it amazing I hope you will enjoy it Neonatal pain policy.pdf

Twitter is really great some time. Check out this discussion started by @AllThingsNeonatal about paralytics for intubation!

Is there anyone using clarytromycine in newborn ? reference ? dose ?

Continuing a topic started on twitter, I would like to ask the 99nicu community. What muscle relaxant do you use in preterms and neonates primarily? Tell us about your experiences? What dose do you use?

Hi 99ers, May I plant a hypothetical scenario to prompt a discussion around the number of steroid courses (DART/Durand etc) to promote extubation. An ex 23 weeker, now 6 weeks old, extubated onto FDCPAP (FiO2 0.7) following second DART regime, but O2 now climbing and now consistently > 0.9 (3 days post end of previous DART). Gaining weight, Diuretics, Ureaplasma -ve, Azithromycin trialled, compensated gases and evolving PIE. Would you reduce your saturation limits and tolerate the high FiO2 requirement, commence a third course of steroid prior to intubation, intubate and then start a 3rd course. Would you ever consider a fourth trial of steroids? Thank…